What studies found
In many tissues, NAD+ levels drop with age. Human trials mostly used the precursors NR and NMN, which can raise NAD+ levels, but health effects in people are unclear. Lifespan results come from animal studies only. Studies of swallowed NAD+ itself are still under way.
How much is in our products
| Product | Amount |
|---|---|
| Liposomal NAD+ | 500 mg liposomal NAD+ per 2-capsule serving |
In studies: Most human trials used the precursors NR or NMN, not NAD+ itself; our guide doesn't list their doses.
We can't compare yet, because human trials mostly tested precursors rather than NAD+ itself.
Who should take care
There isn't enough safety research for pregnancy or breastfeeding, and it's for adults only. NAD+ precursors were well tolerated in human studies, but long-term data are limited. Possible side effects include upset stomach, nausea or headache.
Talk to your doctor or pharmacist before starting a supplement if you take any medicine, are pregnant or breastfeeding, or have a health condition.
Read more in our guides
Sources
- Freeberg KA, et al. 2023. Dietary supplementation with NAD+-boosting compounds in humans: current knowledge and future directions
- ClinicalTrials.gov. A clinical trial to assess the absorption, safety, and efficacy of an oral nicotinamide adenine dinucleotide (NAD+) supplement in healthy adults (NCT07692633)
This page is for general education and isn't medical advice. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.