What studies found
Dozens of small human studies, mostly in healthy volunteers, found that broccoli sprout and seed preparations can raise the body's own detox enzymes modestly. Results on other health measures are mixed, and changes in lab markers haven't been shown to lead to real-world benefits. Without the plant enzyme myrosinase, your gut bacteria convert only a small, variable share of glucoraphanin into sulforaphane, about 5% on average in one study, with wide differences between people.
How much is in our products
| Product | Amount |
|---|---|
| DIM SGS+ | 25 mg per capsule (label allows 1–2 capsules daily) |
In studies: About 25–800 micromoles of glucoraphanin or sulforaphane a day in human studies, for days to 12 weeks.
Our 25 mg works out to at most about 57 micromoles of glucoraphanin, near the low end of studied amounts, and the label lists no myrosinase, so how much becomes sulforaphane varies from person to person.
Who should take care
Possible side effects include a bitter taste, gas, upset stomach or loose stools. A small safety study found no significant side effects at 25–100 micromoles a day. There isn't enough research for pregnancy or breastfeeding, and DIM SGS+ isn't for use while pregnant, trying to conceive or breastfeeding.
Talk to your doctor or pharmacist before starting a supplement if you take any medicine, are pregnant or breastfeeding, or have a health condition.
Read more in our guides
Sources
- Fahey JW, Kensler TW 2021. The challenges of designing and implementing clinical trials with broccoli sprouts… and turning evidence into public health action. Frontiers in Nutrition
- Marino M, et al. 2021. An overview of registered clinical trials on glucosinolates and human health: the current situation. Frontiers in Nutrition
- Shapiro TA, et al. 2006. Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: a clinical phase I study. Nutrition and Cancer
This page is for general education and isn't medical advice. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.